Increasing Colonoscopy Compliance Using a Blood-Based Risk Assessment Test for Colorectal Cancer

Chun Ren Lim, Mohamad Hasyim Mohd Sharil Sim, Eng Lok Seow, Prashanta Kumar Das, David Frederick Harris, Michelle Mei Lin Lee, Choong-Chin Liew, Robert Burakoff


ColonSentry® is a minimally invasive, blood-based risk assessment test for colorectal cancer. The test is used to increase patient compliance with colonoscopy. Many physicians have inquired about the incidence of non-malignant lesions found in patients after colonoscopy prompted by an increased risk score on the ColonSentry test. Here we report on the colonoscopy results of five patients with increased ColonSentry risk scores. Of those five patients, three were determined to have polyps, one of which was pre-malignant.


ColonSentry; Colorectal cancer; Biomarkers; Colonoscopy

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[1] Hagga, F. A., & Boushey, R. P. (2009). Colorectal cancer epidemiology: Incidence, mortality, survival and risk factors. Clinics in Colon and Rectal Surgery, 22(4), 191- 197.

[2] American Cancer Society. (2011). Colorectal Cancer Facts & Figures 2011— 2013. Atlanta: American Cancer Society.

[3] American Society for Gastrointestinal Endoscopy. (2011). Complications of Colonoscopy. Gastrointestinal Endoscopy, 74, 745-752.

[4] Marshall, K.W., Mohr, S., Khettabi, F. E., Nossova, N., Chao, S., Bao, W.,…Liew, C. C. (2010). A blood-based biomarker panel for stratifying current risk for colorectal cancer. International Journal of Cancer, 126, 1177-1186.

[5] Yip, K.T., Das, P. K., Suria, D., Lim, C. R., Ng, G. H. & Liew, C. C. (2010) A case-controlled validation study of a blood-based seven-gene biomarker panel for colorectal cancer in Malaysia. Journal of Experimental & Clinical Cancer Research, 29, 128-134.



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