Actinidic Archaea and Viroids Related Hepato-Gastrointestinal Syndrome

Ravikumar Kurup A., Parameswara Achutha Kurup

Abstract


AbstractBackground: Endogenous digoxin has been related to the pathogenesis of cirrhosis liver, ulcerative colitis, irritable bowel syndrome and peptic ulcer disease. The possibility of endogenous digoxin synthesis by archaea with a mevalonate pathway and cholesterol catabolism was considered.Methods: 10 cases each of cirrhosis liver, ulcerative colitis, irritable bowel syndrome and peptic ulcer disease before starting treatment and 10 age and sex matched healthy controls from general population were chosen for the study. Cholesterol substrate was added to the plasma of the patients and the generation of cytochrome F420, free RNA, free DNA, polycyclic aromatic hydrocarbon, hydrogen peroxide, serotonin, pyruvate, ammonia, glutamate, cytochrome C, hexokinase, ATP synthase, HMG CoA reductase, digoxin and bile acids were studied. The changes with the addition of antibiotics and cerium to the patient’s plasma were also studied. The statistical analysis was done by ANOVA.Results: The parameters mentioned above were increased the patient’s plasma with addition of cholesterol substrate. The addition of antibiotics to the patient’s plasma caused a decrease in all the parameters while addition of cerium increased their levels. Conclusions: An actinide dependent shadow biosphere of archaea and viroids is described in cirrhosis liver, ulcerative colitis, irritable bowel syndrome and peptic ulcer disease contributing to their pathogenesis.

Key words: Archaea; Viroids; Cirrhosis liver; Ulcerative colitis; Irritable bowel syndrome; Peptic ulcer disease


Keywords


Archaea; Viroids; Cirrhosis liver; Ulcerative colitis; Irritable bowel syndrome; Peptic ulcer disease



DOI: http://dx.doi.org/10.3968/j.ans.1715787020110402.670

DOI (PDF): http://dx.doi.org/10.3968/g2148

DOI (indexed/included/archived): http://dx.doi.org/10.3968/g4682

Refbacks

  • There are currently no refbacks.


Copyright (c)




Share us to:   


Reminder

We are currently accepting submissions via email only.

The registration and online submission functions have been disabled.

Please send your manuscripts to ans@cscanada.net,or  ans@cscanada.org  for consideration. We look forward to receiving your work.

 

 Articles published in Advances in Natural Science are licensed under Creative Commons Attribution 4.0 (CC-BY).

 ADVANCES IN NATURAL SCIENCE Editorial Office

Address: 1055 Rue Lucien-L'Allier, Unit #772, Montreal, QC H3G 3C4, Canada.

Telephone: 1-514-558 6138
Website: Http://www.cscanada.net; Http://www.cscanada.org
E-mail:caooc@hotmail.com; office@cscanada.net

Copyright © 2010 Canadian Research & Development Centre of Sciences and Cultures